Chloride titration. The CMT 10 chloride (Radiometer, Copenhagen, Denmark) titrator is used specifically for the determination of chloride content in the serum. During titration, silver ions are generated at the silver anode, located at the bottom of the titration vessel. The end point is detected potentiometrically by an electrode pair comprising a silver indicator electrode and mercury-mercurous sulphate reference electrode. The instrument needs 10 ml of serum.